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 | Acne in General 
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Acne
is a chronic inflammatory disorder that occurs in the adolescent as well
as the adult. It involves a variety of lesions originating from the pilo-sebaceous
follicle. Pilo-sebaceous follicles exist all over the body: the face,
thorax and back. These are the primary seat of polymorphic juvenile acne
and contain a great number of them.
A) There
are three types of follicles:
- Vellus
Follicle: represented by a tiny hair and a tiny gland. This type of
follicle, although responsible for surface oil, plays no part in the
acne process.
- Sebaceous
Follicle: the fine hair lies within a wide canal filled with keratinized
cells. The sebaceous gland is large and multi-lobulated.
- The sebaceous
follicle plays the key role in acne formation, and is found in great
numbers on the face, back and chest.
- Terminal
Hair Follicle: the thick hair fills the canal of the follicle completely.
This type of follicle does not develop acne.
B) The Sebaceous
Gland
The size of the sebaceous gland enlarges as the gland produces more sebum.
In an acne case the sebaceous gland, which on normal skin is approximately
1/10 mm. large, increases in size up to four times. For example, in acne
conglobata, the most severe type of acne, it is not uncommon to find oil
glands which are enlarged ten times. In aged skin, oil glands can enlarge
due to atrophy rather than oil secretion - in fact, the amount of oil produced
decreases with age.
C) Sebum
Sebocytes are produced within the sebaceous glands and form the sebum
which, together with horny cells, are responsible for comedo-formation.
The lipids produced by the sebocytes take approximately one month to come
to the skin surface.
Some of the components of sebum are: free fatty acids, triglycerides,
esters, squalene, glycerides and cholesterin. Bacteria and micro-organisms
such as staphyloccocus corinebacterium acne, as well as pityrosporum (fungus),
are part of the natural flora of the pilosebaceous canal. In case of acne
they produce lipase (enzymes) and split glycerides and triglycerides into
free fatty acids. This, in turn, is irritating and can produce an inflammation
of the follicular epithelium.
Pathogenic Factors
- Obstruction
of follicular orifice with keratinized cells, sebum and debris.
- Hypersecretion
of sebaceous gland.
- Increased
production of free fatty acids due to bacterial activity.
- Formation
of micro-comedones, closed or open comedones.
- Comedone-created
pressure on follicular wall, which ruptures.
- Seepage
of dead cells and sebum into dermis results in papule, pustule and/or
nodule formation, depending on the depth of injury.
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 |  |  | Causes Contributing to Acne A) Internal:
1. Genetic
2. Hormonal
3. Stress (emotional)
4. Poor diet
5. Certain drugs (e.g. cortisone)
B) External:
1. Lack of personal hygiene'
2. Topical pressure or friction through restrictive clothing
3. Comedogenic creams and cosmetics
In most cases acne is the result of an internal malfunction manifesting as
a symptom on the face, chest and back. This is often aggravated externally through
improper management and the wrong kinds of products.
Appearance
1. Thick, coarse skin with extended follicular orifices
2. Oily, shiny surface
3. Blocked orifices and small white lumps under skin - open and closed comedones
4. Papules that are red and swollen
5. Pustules with white or yellow-tinged centers
6. Deep-seated painful lumps (nodules and/or cysts)
Touch
1. Rough
2. Swollen (inflamed)
3. Greasy
The symptoms in #4 and #5 above describe a classic poly-morphic acne condition.
This may, however, differ with each individual. Some people may develop only
one or two types of lesions, and the skin surface may often appear dry due to
excessive use of drying agents.

|  |  | Home Care Regimen for Acne Skin A) a.m.
- Wash with purifying, cleansing product.
- Apply antiseptic lotion (Oily Skin Lotion).
- Moisturize with a product containing antiseptic and healing properties
(e.g. Creme Hydratane or Lurophase).
- Omit makeup if possible.
B) p.m.
- Cleanse as above.
- Gently apply a deep-pore cleanser over comedones (e.g. Silica Soap); repeat
2-3
times weekly.
- Apply antiseptic lotion as above.
- Apply anti-bacterial serum together with a cell reproducing cream .
C) Weekly
- Steam over comphrey or thyme herbs.
- Follow with application of absorbent mask.
- Exfoliate 2-3 times weekly.
After treatment has been introduced, an initial worsening of the condition
can occasionally be observed. This is normal, as all existing acne lesions have
to work through their cycles. Clients should be made aware of this transition,
and weekly deep-cleansings are suggested.

|  |  | Products and Active Ingredients For decades, cosmetic ingredients have been tested for their levels of comedo-genicity;
the rabbit's ear has been used for these studies. Results are often imprecise,
however, since the rabbit ear differs histologically from human skin. In addition,
ingredients tested individually can show different readings than when combined.
Each individual's tolerance to a specific product may also vary.

|  |  | The following substances are useful for the treatment of acne
- Lavender: which is both antiseptic and soothing.
- Thyme: which is bactericidal, produces hyperemia and stimulates peripheral
blood
circulation.
- Mint, thyme and camphor: act as solvents on fats.
- Yeast, mineral extracts, halibut liver oil and trace elements.

|  |  | Diet and Dietary Supplements for Acne Skin
- Avoid fried foods, butter, cheeses, whole milk, ice cream, rich salad dressings,
chocolate, fatty meats, anything from cocoa or coffee beans, other stimulants,
sweets and processed nut products.
- Include fresh fruit, plenty of water, fresh and cooked vegetables, lean
meats, broiled fish, chicken, whole-grain cereals and other complex carbohydrates.
The diet should allow regular bowl movements.
- Foods containing bromides, iodine and caffeine stimulate the endocrine
system, which in turn increases the amount of oil produced by the sebaceous
gland.
- Vitamin A and Zinc supplements can be helpful, but be sure the client is
aware of the proper dosage.

|  |  | Hormonal Effects on Acne Skin A) Puberty
One of the first events in that period of life known as puberty is the secretion
of certain gonadotrophic hormones by the anterior pituitary gland. The target
organs of these gonadotrophins are the gonads, i.e. the ovaries in woman or
the testes in man. In addition, the adrenal cortex is stimulated to action at
around the same time. Both these glands, the adrenal cortex and the gonads,
are encouraged to excrete large quantities of steroid hormones into the circulatory
system. In the male, the influence of adrenal hormones on bodily changes is
overshadowed by the action of the testicular hormones. In the female, the female
estrogens produced by the ovaries work in conjunction with the male androgens
from the adrenal cortex to create secondary sex characteristics. This sudden
surge of male hormones (called androgens) in both sexes results in bodily hair
growth as well as increased oil flow from the sebaceous glands. This increase
in oil flow does not automatically lead to acne, but it sets the stage and no
acne is possible without it. Only a small amount is needed to prod the oil glands,
and it is impossible to distinguish the androgen levels of acne patients from
those of clear skinned types.
B) Heredity
People with chronically oily skin and lingering acne have been found to harbor
an especially active enzyme that converts testosterone, one of the androgens,
into a more potent form called dihydrotestosterone. This is the factor directly
responsible for releasing more oil. It is thought that if the effects of dihydro-testosterone on the sebaceous glands could be counteracted then acne could be controlled. The challenge lies in accomplishing this without tampering with the body's normal hormone makeup. Genes are also believed to play a stage setting role, since acne and its degree of severity often run in families. Heredity can help determine the amount of oil your body produces, the kind of bacteria nesting in your glands, the strength of your follicle walls, and other factors linked to either your resistance or your susceptibility.
C) Acne in Adulthood
Occasionally the onset of acne in adulthood can signal the presence of pituitary,
adrenal, or ovarian tumors. The condition will usually be accompanied by other
signs of excess androgen or erratic hormone activity: irregular menstrual periods, the growth of facial hair, and deepening of the voice. Other factors, if not direct causes, may aggravate an already existing case of acne. In cases of anxiety and stress, the body signals the pituitary gland to release more of its hormones to meet the challenge. These, in turn, stimulate the adrenal cortex to pour more androgens into the bloodstream. Since people vary in their tolerance to
extra androgens, not everyone under pressure will have an acne flare-up. But
stress will put those who are susceptible at higher risk. Stress can also lead
to nervous scratching and picking of the face, which can irritate pimples and
drive them deeper into the skin. To complicate matters, it has been found that
the output of fatty acids is also increased during stress.
D) Pregnancy and Menopause
Hormonal changes in women during pregnancy and menopause are also contributing
factors in oil secretion and hair growth since hormones produced by the ovaries
have an inhibiting effect on the anterior pituitary. If secretion from the ovaries is affected in any way, there may be lack of control over the pituitary gland. This can result in a hyperstimulation by pituitary hormones of the adrenal cortex, which in turn can produce an excess of androgens, which in turn can produce an excess of androgens, which can lead to excessive oil production and hair growth.

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